Detail
Name Apixaban
Molecular Formula C25H25N5O4
Molecular Weight 459.50
CAS Registry Number 503612-47-3
White to off-white powder
Water≤1.0%
Residue on ignition≤0.5%
Single impurity: ≤0.5%
Total other impurities:≤1.0%
Heavy metals≤20ppm
Assay (HPLC)98.0%～101.0%
An oral selectivity factor Xa inhibitor,antithrombotics.
Related intermediates:
5,6-Dihydro-3-(4-morpholinyl)-1-(4-nitrophenyl)-2(1H)-pyridinone 503615-03-0
1-(4-Iodophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one 473927-69-4