Ivermectin

Section 1: Chemical Product and Company Identification

Product Name: Ivermectin

CAS#: 70288-86-7

RTECS: IH7891500

Synonym: 22,23-Dihyroavermectin B1

Chemical Name: Ivermectin

Supplier: KINFON PHARMACHEM CO.,LTD

F4, No.5 Torch Ave, JLP Dist, Chongqing 400080, China

website: www.echemix.com     email: sales@echemix.com

Section 2: Composition and Information on Ingredients

Name CAS # % by Weight

Ivermectin 70288-86-7 100

Toxicological Data on Ingredients: Ivermectin: ORAL (LD50): Acute: 29.5 mg/kg [Mouse].

Section 3: Hazards Identification

Potential Acute Health Effects:

Slightly hazardous in case of skin contact (irritant), of eye contact (irritant). Severe over-exposure can result in death.

Potential Chronic Health Effects:

CARCINOGENIC EFFECTS: Not available.

MUTAGENIC EFFECTS: Classified None. for human. Non-mutagenic for mammalians.

TERATOGENIC EFFECTS: Not available.

DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/male [POSSIBLE]. Classified

Reproductive system/toxin/female [None.].

Repeated exposure to an highly toxic material may produce general deterioration of health by an accumulation in one or many human organs.

Section 4: First Aid Measures

Eye Contact: No known effect on eye contact, rinse with water for a few minutes.

Skin Contact:

After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin

with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin.

Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing before reusing.

Serious Skin Contact: Not available.

Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention.

Serious Inhalation:

Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek medical attention.

Ingestion:

Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention.

Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: May be combustible at high temperature.

Auto-Ignition Temperature: Not available.

Flash Points: Not available.

Flammable Limits: Not available.

Products of Combustion: Not available.

Fire Hazards in Presence of Various Substances: Not available.

Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of mechanical impact: Not available.

Risks of explosion of the product in presence of static discharge: Not available.

Fire Fighting Media and Instructions:

SMALL FIRE: Use DRY chemical powder.

LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Special Remarks on Fire Hazards: Not available.

Special Remarks on Explosion Hazards: Not available.

Section 6: Accidental Release Measures

Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container.

Large Spill: Use a shovel to put the material into a convenient waste disposal container.

Section 7: Handling and Storage

Precautions:

Keep locked up Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk; evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. Wear suitable protective clothing If ingested, seek medical advice immediately and show the container or the label.

Storage:

Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly closed. Keep in a cool, well-ventilated place. Highly toxic or infectious materials should be stored in a separate locked safety storage cabinet or room.

Section 8: Exposure Controls/Personal Protection

Engineering Controls:

Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.

Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.

Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist

BEFORE handling this product.

Exposure Limits: Not available.

Section 9: Physical and Chemical Properties

Physical state and appearance: Solid.

Odor: Not available.

Taste: Not available.

Molecular Weight: Not available.

Color: Off-white.

pH (1% soln/water): Not applicable.

Boiling Point: Not available.

Melting Point: Not available.

Critical Temperature: Not available.

Specific Gravity: Not available.

Vapor Pressure: Not applicable.

Vapor Density: Not available.

Volatility: Not available.

Odor Threshold: Not available.

Water/Oil Dist. Coeff.: Not available.

Ionicity (in Water): Not available.

Dispersion Properties: See solubility in water, acetone.

Solubility: Soluble in acetone.

Very slightly soluble in hot water, n-octanol. Insoluble in cold water, methanol.

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Not available.

Incompatibility with various substances: Not available.

Corrosivity: Non-corrosive in presence of glass.

Special Remarks on Reactivity: Not available.

Special Remarks on Corrosivity: Not available.

Polymerization: Not available.

Section 11: Toxicological Information

Routes of Entry: Inhalation. Ingestion.

Toxicity to Animals: Acute oral toxicity (LD50): 29.5 mg/kg [Mouse].

Chronic Effects on Humans:

MUTAGENIC EFFECTS: Classified None. for human. Non-mutagenic for mammalians.

DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/male [POSSIBLE]. Classified

Reproductive system/toxin/female [None.].

Other Toxic Effects on Humans: Slightly hazardous in case of skin contact (irritant).

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans: Not available.

Special Remarks on other Toxic Effects on Humans: Not available.

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:

Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.

Toxicity of the Products of Biodegradation: Not available.

Special Remarks on the Products of Biodegradation: Not available.

Section 13: Disposal Considerations

Waste Disposal:

Section 14: Transport Information

DOT Classification: CLASS 6.1: Poisonous material.

Identification: : Toxic solids n.o.s. (Ivermectin) : UN2811 PG: II

Special Provisions for Transport: Not available.

Section 15: Other Regulatory Information

Federal and State Regulations: TSCA 8(b) inventory: No products were found.

Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).

Other Classifications:

WHMIS (Canada): CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC).

DSCL (EEC):

R40- Possible risks of irreversible effects.

R62- Possible risk of impaired fertility.

HMIS (U.S.A.):

Health Hazard: 3

Fire Hazard: 1

Reactivity: 0

Personal Protection: E

National Fire Protection Association (U.S.A.):

Health: 3

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment:

Gloves.

Lab coat.

Dust respirator. Be sure to use an

approved/certified respirator or equivalent. Wear appropriate respirator when ventilation is inadequate.Safety glasses.

Section 16: Other Information

References: Not available.

Other Special Considerations: Not available.

All information and instructions provided in this Material Safety Data Sheet

(MSDS) are based on the current state of scientific and technical knowledge. And above information is only for reference.