Hydroxylapatite
Section 1: Chemical Product and Company Identification
Product Name: Hydroxylapatite
Synonyms： : Calcium phosphate hydroxide; Durapatite; Calcium phosphate tribasic.
CAS#: 1306-06-5
MF: Ca5HO13P3
MW: 502.31
EINECS: 215-145-7
Supplier: KINFON PHARMACHEM CO.,LTD
F4, No.5 Torch Ave, JLP Dist, Chongqing 400080, China
website: www.echemix.com email: sales@echemix.com
Section 2: Composition and Information on Ingredients
Chemical Name： Hydroxylapatite
CAS No. 1306-06-5
Content: 96%
Section 3: Hazards Identification
Appearance: white powder.
Caution! May cause eye, skin, and respiratory tract irritation.
Target Organs: None known.
Potential Health Effects
Eye: May cause eye irritation.
Skin: May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation: May cause respiratory tract irritation. May be harmful if inhaled.
Chronic: No information found.
Section 4: First Aid Measures
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. If irritation develo ps, get medical aid.
Skin: Immediately flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion: Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of
milk or water. Get medical aid if irritation or symptoms occur.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other
symptoms appear.
Notes to Physician: Treat symptomatically and supportively
Section 5: Fire and Explosion Data
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting
the upper and lower eyelids. If irritation develo ps, get medical aid.
Skin: Immediately flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion: Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of
milk or water. Get medical aid if irritation or symptoms occur.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other
symptoms appear.
Notes to Physician: Treat symptomatically and supportively.
Section 6: Accidental Release Measures
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Avoid
generating dusty conditions. Provide ventilation. Do not let this chemical enter the environment
Section 7: Handling and Storage
Handling: Use only in a well-ventilated area. Minimize dust generation and accumulation. Avoid
contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage: Store in a cool, dry place. Store in a tightly closed container.
Section 8: Exposure Controls/Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped with an
eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations
low.
Exposure Limit:
ACGIH:none listed
NIOSH:none listed
OSHA - Final PELs:none listed
OSHA Vacated PELs: Hydroxylapatite: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European
Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if
exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9: Physical and Chemical Properties
Physical State: Powder
Appearance: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:1700 deg C
Decomposition Temperature:Not available.
Solubility: practically insoluble
Specific Gravity/Density:Not available.
Molecular Formula:HCa5O13P3
Molecular Weight:502.31
Section 10: Stability and Reactivity Data
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, dust generation.
Incompatibilities with Other Materials: Strong oxidizing agents.
Hazardous Decomposition Products: Not known.
Hazardous Polymerization: Will not occur.
Section 11: Toxicological Information
RTECS#:
CAS# 1306-06-5: MY8434000
LD50/LC50:
CAS# 1306-06-5:
Oral, mouse: LD50 = >99500 mg/kg;
Oral, rat: LD50 = >25350 mg/kg;
Carcinogenicity:
CAS# 1306-06-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology: No information found
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: Mutagenic effects have occurred in humans.
Neurotoxicity: No information found
Other Studies:
Section 12: Ecological Information
Ecotoxicity: No data available. No information available.
Environmental: No information available.
Physical: No information available.
Other: Do not empty into drains.
Section 13: Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts
261.3. Additionally, waste generators must consult state and local hazardous waste regulations
to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14: Transport Information
US DOT:NOT REGULATED FOR DOMESTIC
Canada TDG:NOT REGULATED
Section 15: Other Regulatory Information(in China)
US FEDERAL
TSCA
CAS# 1306-06-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
Section 313 No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are listed as Priority Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 1306-06-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ.
California Prop 65
California No Significant Risk Level: None of the chemicals in this product are listed.
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 1306-06-5: 0
Canada - DSL/NDSL
CAS# 1306-06-5 is listed on Canada's DSL List.
Canada - WHMIS
not available.
This product has been classified in accordance with the hazard criteria of the Controlled Products
Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
Section 16: Other Information
References: Not available.
Other Special Considerations: Not available.
All information and instructions provided in this Material Safety Data Sheet (MSDS) are based on the current state of scientific and technical knowledge. And above information is only for reference.