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Name                             Apixaban  

Molecular Formula      C25H25N5O4  

Molecular Weight         459.50  

CAS Registry Number      503612-47-3  


White to off-white powder

Water≤1.0%

Residue on ignition≤0.5%

Single impurity: ≤0.5%

Total other impurities:≤1.0%

Heavy metals≤20ppm

Assay (HPLC)98.0%~101.0%



An oral selectivity factor Xa inhibitor,antithrombotics.



Related intermediates:

5,6-Dihydro-3-(4-morpholinyl)-1-(4-nitrophenyl)-2(1H)-pyridinone    503615-03-0

1-(4-Iodophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one           473927-69-4